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Smallpox

Latest News New on the Site
May 8
Smallpox drug does well in first human safety test
Apr 21
CDC reports vaccinia infections in lab workers
Mar 7
CDC retires one old smallpox vaccine, keeps another
Feb 8
US military switching to new smallpox vaccine
Sep 4
FDA approves Acambis smallpox vaccine
Jun 5
Danish firm wins US contract for new smallpox vaccine
May 18
WHO postpones smallpox virus destruction by 4 years
FDA panel recommends smallpox vaccine approval
May 17
CDC reports on soldier's son who had severe vaccinia infection
May 4, 2007
CDC reports sexual transmission of vaccinia
Apr 25, 2007
HHS offers plan for defense against biological threats
Apr 18, 2007
Danish firm expects to sell smallpox vaccine to US
Mar 19, 2007
Son of vaccinated soldier has severe vaccinia infection
Dec 11, 2006
CDC rates hospital bioterrorism preparedness
Jun 26, 2006
Soldier's death possibly linked to shots for smallpox, flu
Jun 5, 2006
WHO defers decision on destroying smallpox virus
Dec 14, 2005
Study shows few serious problems among smallpox vaccinees
Aug 16, 2005
US seeks stockpile of safer smallpox vaccine
Aug 11, 2005
Persistence of smallpox immunity may have protected against monkeypox in 2003
Jun 1, 2005
WHO smallpox vaccine reserve gains support
Apr 29, 2005
Smallpox shots caused unexpected side effects in CDC study
Mar 11, 2005
IOM says poor communication hurt CDC smallpox efforts
Feb 24, 2005
FDA approves VIG for smallpox shot complications
Jan 19, 2005
Smallpox exercise shows shortages of vaccine
Dec 10, 2004
US pledges smallpox vaccine for world stockpile
    
Genetic basis for adverse events after smallpox vaccination
From J Infect Dis, published online May 2 with accompanying commentary (below)

Learning to appreciate our differences
Commentary in J Infect Dis, published online May 2

Single-dose safety and pharmacokinetics of ST-246, a novel orthopoxvirus egress inhibitor
From May Antimicrob Agents Chemother

Laboratory-acquired vaccinia exposures and infections--United States, 2005-2007
From Apr 18 MMWR

Vaccination of BALB/c mice with E coli-expressed vaccinia virus proteins A27L, B5R, and D8L protects mice from lethal vaccinia virus challenge
From Apr J Virol

Short- and long-term immunogenicity and protection induced by non-replicating smallpox vaccine candidates in mice and comparison with the traditional 1st generation vaccine
From Mar 25 Vaccine

Quality assessment of nonanthrax vaccination data in the Defense Medical Surveillance System, 1998-2004
From Mar 17 Vaccine

Smallpox: Current, comprehensive information on pathogenesis, microbiology, epidemiology, diagnosis, treatment, and prophylaxis
CIDRAP-authored overview, updated Mar 9


New generation smallpox vaccines: a review of preclinical and clinical data
From Rev Med Virol, published online Feb 19

Immune responses to the smallpox vaccine given in combination with ST-246, a small molecule inhibitor of poxvirus dissemination
From Feb 13 Vaccine

Immunogenicity and protection efficacy of subunit-based smallpox vaccines using variola major antigens
From Feb 5 Virology

Vaccinia viruses with mutations in the E3L gene as potential replication-competent, attenuated vaccines: intral-nasal vaccination
From Jan 30 Vaccine

Clonal vaccinia virus grown in cell culture fully protects monkeys from lethal monkeypox challenge
From Jan 24 Vaccine

Traditional smallpox vaccination with reduced risk of inadvertent contact spread by administration of povidone iodine ointment
From Jan 17 Vaccine

Antibody profiling by proteome microarray reveals the immunogenicity of the attenuated smallpox vaccine modified vaccinia virus Ankara is comparable to that of Dryvax
From Jan J Virol

Orthopoxvirus detection in environmental specimens during suspected bioterror attacks: inhibitory influences of common household products
From Jan Appl Environ Microbiol

A novel, killed-virus nasal vaccinia vaccine
From Clin Vaccine Immunol, published online Dec 5

Persistence of vaccinia at the site of smallpox vaccination
From Clin Infect Dis, published online Nov 26

Smallpox vaccination and ischemic coronary events in healthy adults
From Dec 5 Vaccine

Identification of novel antipoxviral agents: mitoxantrone inhibits vaccinia virus replication by blocking viron assembly
From Dec J Virol

Safety, immunogenicity and protective efficacy in mice of a new cell-cultured Lister smallpox vaccine candidate
From Nov 28 Vaccine

 

Provided by the Center for Infectious Disease Research and Policy (CIDRAP), University of Minnesota.


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